Non sedating oral antihistamine updating old oak cabinets

Most of the studies reviewed used doses that were twice the recommended amount -- 50 milligrams -- of diphenhydramine, the active ingredient in Benadryl and other first-generation "sedating" allergy medications.

"We're not saying that there's not a difference," says lead researcher Bruce G.

Antihistamines are very good at relieving symptoms of an allergic reaction, such as: First-generation antihistamines were developed more than seventy years ago and are still in widespread use today.

They act on histamine receptors in the brain and spinal cord and in the rest of the body (called the periphery).

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Antihistamines are a class of agents that block histamine release from histamine-1 receptors and are mostly used to treat allergies or cold and flu symptoms, although some first-generation antihistamines may also be used for other conditions.They also act on muscarinic, alpha-adrenergic, and serotonin receptors.This means that first-generation antihistamines are more likely to cause side effects such as sedation, dry mouth, dizziness, low blood pressure, and a rapid heart-beat.Second generation antihistamines were developed in the 1980s and are much less sedating than first-generation antihistamines.They act on histamine-1 receptors in the periphery and are unlikely to penetrate the brain, so are less likely to cause side effects or interact with drugs.

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